pentobarbital will decrease the level or effect of pimavanserin ort affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Datorskärm. Avoid coadministration if possible. Monitor for reduced pimavanserin efficacy. An increase in pimavanserin dosage may be needed.In primates, exposure to 3 hours of ketamine that produced a light surgica